Tottenham have won eight league games in a row but they'll have their work cut out to finish the season with five more wins and Spurs will also have to depend on Chelsea dropping points between now and the end of the season.
At the very least Champions League qualification looks nailed on, as does finishing above Arsenal for the first time in 22 years, although Pochettino said that would not be uppermost in their mind in Sunday's north London derby.
Asked if the chance to ensure supremacy over Arsenal might fire up his players too much, Pochettino called for calm. It is certainly serious enough to keep him out for who knows how long, we won't know until we diagnose it. Our focus is trying to win. It's more about us building confidence, building faith that we can win, generating that winning mentality.
"To win big trophies and achieve big things, your mentality must be bigger". "I think the referee made the wrong decision, I don't think he was fearless enough".
In Saturday's FA Cup semi-final against Chelsea, Tottenham Hotspur were undone by moments of magic from Eden Hazard and Nemanja Matic. "I think it was a great opportunity to show we are focused on us and trying to improve our game, and to fight when we are under pressure".
Spurs are now four points behind Chelsea with five games to play, and the 25-year-old playmaker suggests his team have learned from past mistakes.
"We are showing we learnt a lot from last season".
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"The first half was a bit more hard".
The Argentine brought on Son Heung-min and Moussa Sissoko for Moussa Dembele and Victor Wanyama who was fortunate not to be sent off in the first half.
Dele Alli should have put Spurs ahead when he met Kyle Walker's cross three yards out, only to side foot his effort across goal and wide.
"Yes, it was a very big goal". The first half was even but we dominated the second half.
Yet the way they persevered against an obdurate Palace side to grind out three crucial points it was hard to disagree with the Argentine manager, who has turned Tottenham's young side into one consistently challenging near the top. "The challenge is to keep going". "It is always better to win but it is true now it is a big derby, perhaps the last at White Hart Lane and I think it will be an exciting game".
Sakho was stretchered off midway through the second half in Palace's 1-0 loss to Tottenham on Wednesday night, with fears he could have suffered ligament damage.
"We knew we had to bounce back after the weekend".