Guardiola's comment following his side's 1-0 win against Chelsea at Stamford Bridge brought smiles from those present, but Pochettino was not amused by the tag that he views as disrespectful to his players.
Before the global break, Guardiola named "the Harry Kane team" alongside Chelsea and Manchester United as City's title rivals after the England worldwide scored six goals in four Premier League games in September to fire Tottenham into third behind the Manchester clubs.
Speaking to reporters today, Pochettino admitted that he personally took no offence to the remarks but described them as "unnecessary" and "disrespectful" to his players and fans.
"I take that situation, that didn't affect me but the reality is it was very disrespectful for many people and it's hard to understand because he was part of the big success at Barcelona with [Lionel] Messi at his best, and I never said it was "the Messi team" - I always said it was Barcelona or Pep Guardiola".
"I think last season, the guy who appreciated the way they play the most was me", he said.
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"I respect a lot what Tottenham have done in the last two or three years". We need to win trophies to say it's a massive period for us.
'There is a lot of credit in the way they play, in the way they want to show their football in the Premier League, the way they are always attacking.
"I respect his opinion but it's a sad comment". For me, Harry Kane is one of the best strikers and it's important that our position is clear, to be calm and not be aggressive with our opponents.
Pochettino was asked whether he had spoken to Guardiola about the comment. Maybe after the press conference he calls me.
'From the times I spoke with him, maybe my English is not so well, but I was never disrespectful to my colleague. "I'm sure I will reply", he added. Of course. We have a very good relationship. But it's sad. A sad comment. It's not him. He's a great manager. It doesn't help him.
"But I said it because he scored two goals more against Huddersfield and a goal for the national team and another goal for the national team". It's always important for us to talk, create a good atmosphere for everyone to be a part and feel happy here.